The United States Department of Health and Human Services (HHS) is responsible for a wide range of regulations that govern various aspects of healthcare and public health in the country. Some of the key regulations enforced by the Department of Health include:

1. The Health Insurance Portability and Accountability Act (HIPAA): HIPAA sets standards for the protection of individuals' health information and requires healthcare providers, health plans, and other entities to safeguard the privacy and security of this information.

2. The Food and Drug Administration (FDA) regulations: The FDA regulates the safety and effectiveness of food, drugs, medical devices, and cosmetics. It also oversees the labeling, advertising, and marketing of these products to ensure they are safe for consumer use.

3. The Centers for Disease Control and Prevention (CDC) regulations: The CDC sets guidelines and regulations for controlling and preventing the spread of infectious diseases, monitoring public health trends, and promoting healthy behaviors.

4. The Affordable Care Act (ACA): The ACA, also known as Obamacare, includes regulations aimed at expanding access to healthcare coverage, improving the quality of care, and reducing healthcare costs.

5. The Centers for Medicare and Medicaid Services (CMS) regulations: CMS oversees the Medicare and Medicaid programs and sets regulations for reimbursement, quality of care, and fraud prevention.

6. The Public Health Service Act: This act authorizes the HHS to carry out various public health programs and initiatives, including disease prevention, health promotion, and research.

7. The Family and Medical Leave Act (FMLA): The FMLA is a federal law that requires covered employers to provide employees with job-protected leave for certain family and medical reasons.

Overall, the Department of Health enforces regulations that aim to protect the health and well-being of the American public, ensure access to quality healthcare services, and promote public health initiatives. These regulations play a critical role in shaping the healthcare landscape in the United States and are essential for safeguarding the health and safety of individuals and communities.